Paper of the Day 2022

Other Years: 2023

Critical Care Reviews
Paper of the Day 2022

The collection of 365 daily papers posted during 2022

Saturday, December 31st

2022

Anderson. Comprehensive Review of Chest Tube Management. A Review. JAMA Surg 2022;157(3):269-274

Months

December

31st	Respiratory	Anderson. Comprehensive Review of Chest Tube Management. A Review. JAMA Surg 2022;157(3):269-274
30th	Sepsis	Carter. Sepsis and the brain: a review for acute and general physicians. J Clin Med 2022;22(5):392-395
29th	Sepsis	Lim. Phenotyping and Hemodynamic Assessment in Cardiogenic Shock: From Physiology to Clinical Application. Cardiol Ther 2022;11:509–522
28th	Liver	Wang. The pathogenesis and therapeutic strategies of heat stroke-induced liver injury. Crit Care 2022;26:391
27th	Neuro	Zakrison. Review Paper on Penetrating Brain Injury. Ethical Quandaries in the Trauma Bay and Beyond. Ann Surg 2023;277(1):66-72
26th	Resuscitation	Obermaier. Advanced and Invasive Cardiopulmonary Resuscitation (CPR) Techniques as an Adjunct to Advanced Cardiac Life Support. J Clin Med 2022;11(24):7315
25th	Circulatory	Zotzmann. Obstructive Shock, from Diagnosis to Treatment. Rev Cardiovasc Med 2022;23(7):248
24th	Respiratory	Murray . Reverse Triggering: An Introduction to Diagnosis, Management, and Pharmacologic Implications. Front Pharmacol 2022;13:879011
23rd	Neuro	Jabaudon. Inhaled sedation in the intensive care unit. Anaesth Crit Care Pain Med 2022;41(5):101133
22nd	Circulatory	De Backer. How can assessing hemodynamics help to assess volume status?. Intensive Care Med 2022;48:1482-1494
21st	Neuro	Abraham. Understanding and Managing Autonomic Disorders in the Neurocritical Care Unit: A Comprehensive review. Neurol India 2022;70:485-90
20th	Neuro	Spears. Brain death: a clinical overview. J Intensive Care 2022;10:16
19th	Neuro	Wijdicks. Identifying encephalopathies from acute metabolic derangements. J Intern Med 2022;epublished July 9th
18th	Neuro	Marazzi. Updates on aneurysmal subarachnoid hemorrhage: is there anything really new? Arq Neuropsiquiatr 2022;80(5 Suppl 1):80-87
17th	Respiratory	Saavedra. Asynchronies during invasive mechanical ventilation: narrative review and update. Acute Crit Care 2022;37(4):491-501
16th	Neuro	De Stefano. Nonconvulsive status epilepticus following cardiac arrest: overlooked, untreated and misjudged. J Neurol 2022;epublished September 8th
15th	Neuro	Riveros Gilardi. Types of Cerebral Herniation and Their Imaging Features. Radiographics 2019;39(6):1598-1610
14th	Respiratory	Ahmed. Difficult tracheal intubation in critically ill. J Intensive Care 2018;6:4
13th	Circulatory	Muñoz-Rodríguez. Ultrasound Assessment in Cardiogenic Shock Weaning: A Review of the State of the Art. J Clin Med 2021;10(21):5108
12th	Respiratory	Wyatt. Recent advances in the use of high flow nasal oxygen therapies. Front Med 2022;9:1017965
11th	Circulatory	Sams. Adult ECMO in the En Route Care Environment: Overview and Practical Considerations of Managing ECMO Patients During Transport. Curr Trauma Rep 2022;epublished October 20th
10th	Immunology	Luperto. T cell dysregulation in inflammatory diseases in ICU. ICMx 2022;10:43
9th	Imaging	Breitkopf. Lung Sonography in Critical Care Medicine. Diagnostics 2022;12(6):1405
8th	Neuro	Picetti. Perioperative management of severe brain injured patients. Minerva Anestesiologica 2022;88(5):380-9
7th	Renal	He. Sepsis-induced AKI: From pathogenesis to therapeutic approaches. Front Pharmacol 2022;epublished September 15th
6th	Sepsis	Schmitz. Streptococcal toxic shock syndrome in the intensive care unit. Ann Intensive Care 2018;8(1):88
5th	Sepsis	Perea. Optimization of antimicrobial treatment in sepsis. Rev Esp Quimioter 2022;35(Suppl 3):30-33
4th	Neuro	Crawshaw. Medical management of status epilepticus: Emergency room to intensive care unit. Seizure 2020;75:145-152
3rd	Obstetrics	Griffin. Obstetric Disorders and Critical Illness. Clin Chest Med 2022;43(3):471–488
2nd	Sepsis	Rello. Monitoring the Host Immune Response in Sepsis. J Transl Crit Care Med 2022;4:18
1st	Metabolic	Klincová. Malignant Hyperthermia in PICU—From Diagnosis to Treatment in the Light of Up-to-Date Knowledge. Children 2022;9:1692

November

30th	Renal	De Vlieger. Kidney Dysfunction After Traumatic Brain Injury: Pathophysiology and General Management. Neurocrit Care 2022;epublished November 2nd
29th	Circulatory	Messina. Pathophysiology of fluid administration in critically ill patients. ICMx 2022;10:46
28th	Circulatory	Ende. The Diagnosis and Treatment of Postoperative Right Heart Failure. Dtsch Arztebl Int 2022;119(29-30):514–524
27th	Respiratory	Murray. Reverse Triggering: An Introduction to Diagnosis, Management, and Pharmacologic Implications. Front Pharmacol 2022;13:879011
26th	GI	Crosignani. Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review. Ann Intensive Care 2022;12:98
25th	Respiratory	Cheng. Does airway pressure release ventilation offer new hope for treating acute respiratory distress syndrome? J Intensive Med 2022;2(4):241-248
24th	Circulatory	Jozwiak. Alternatives to norepinephrine in septic shock: Which agents and when? J Intensive Med 2022;2(4):223-232
23rd	Neuro	Lindblad. Current state of high‑fidelity multimodal monitoring in traumatic brain injury. Acta Neurochirurgica 2022;epublished October 19th
22nd	COVID-19	Murakami. Therapeutic advances in COVID-19. Nat Rev Nephrol 2022;epublished October 17th
21st	Renal	Chaudhari. Contrast-Induced Acute Kidney Injury: Evidence in Support of Its Existence and a Review of Its Pathogenesis and Management. Int J Nephrol Renovasc Dis 2022;15:253—266
20th	Respiratory	Cesarano. Helmet noninvasive support for acute hypoxemic respiratory failure: rationale, mechanism of action and bedside application. Ann Intensive Care 2022;12(1):94
19th	Paediatrics	Imataka. A Comprehensive Review of Pediatric Acute Encephalopathy. J Clin Med 2022;11(19):59211
18th	Dermatology	Hasegawa. Recent advances in managing and understanding Stevens-Johnson syndrome and toxic epidermal necrolysis. F1000Research 2020;9(F1000 Faculty Rev):612
17th	Renal	Kim. Pathophysiology of Drug-Induced Hyponatremia. J Clin Med 2022;11(19):5810
16th	Respiratory	Thomas. Oxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients: From Pathophysiology to Clinical Practice. JACC Adv 2022;1(3):100065
15th	Respiratory	Chopard. An Update on the Management of Acute High-Risk Pulmonary Embolism. J Clin Med 2022;11(19):4807
14th	Circulatory	Kuroda. Mechanical circulatory support devices and treatment strategies for right heart failure. Front Cardiovasc Med 2022;9:951234
13th	COVID-19	Cavus. Opportunistic Candida Infections in Critical COVID-19 Patients. Polish Journal of Microbiology 2022;71(3):411–419
12th	Neuro	Dono. Gut microbiome and neurocritically ill patients. Neurocrit Care 2022;15(1):1-11
11th	Transfer Medicine	László. Preparing the Patient for ICU Transfer: What Is the Anesthesiologist’s Role?. Curr Anesthesiol Rep 2022;epublished October 3rd
10th	Miscellaneous	Ramos. Subphenotyping of critical illness: where protocolized and personalized intensive care medicine meet. Rev Bras Ter Intensiva 2022;epublished September 12th
9th	Perioperative	Nath. Perioperative management of patients with prosthetic heart valves-A narrative review. Ann Card Anaesth 2022;25:254-63
8th	Renal	Murugan. Fluid Overload and Precision Net Ultrafiltration in Critically Ill Patients. Cardiorenal Med 2022;epublished October 6th
7th	COVID-19	Assouline. Extracorporeal membrane oxygenation in COVID-19 associated acute respiratory distress syndrome: A narrative review. J Intensive Med 2022;epublished October 4th
6th	Respiratory	Zhang. Prone positioning in ARDS patients supported with VV ECMO, what we should explore?. J Intensive Care 2022;10:46
5th	Cardiology	Nägele. Heart Failure After Right Ventricular Myocardial Infarction. Curr Heart Fail Rep 2022;epublished October 5th
4th	Respiratory	Frat. High-flow nasal cannula oxygen therapy in acute hypoxemic respiratory failure and COVID-19-related respiratory failure. J Intensive Med 2022;epublished September 29th
3rd	Toxicology	Voicu. Extracorporeal life support in cardiotoxicant poisoning - a narrative review. Basic Clin Pharmacol Toxicol 2022;epublished October 5th
2nd	Neuro	Midega. Ketamine use in critically ill patients: a narrative review. Rev Bras Ter Intensiva 2022;34(02):287-294
1st	Sepsis	Carter. The management of acute meningitis: an update. Clin Med 2022;22(5):396-400

October

31st	COVID-19	Mehta. A practical update on the management of patients with COVID–19. Clin Med 2022;22(5):468-474
30th	Obstetrics	Hofer. Haemostatic support in postpartum haemorrhage. A review of the literature and expert opinion. Eur J Anaesthesiol 2022;epublished September 23rd
29th	Sepsis	Nederstigt. Potential pandemic pathogens series: Crimean-Congo haemorrhagic fever. Neth J Crit Care July 2022;30(4):131-135
28th	Respiratory	Lius. Hyperoxia in the management of respiratory failure: A literature review. Ann Med Surg 2022;81:104393
27th	Circulatory	Pinsky. Effective hemodynamic monitoring. Crit Care 2022;26(1):294
26th	Hepatology	de Mattos. Albumin administration in patients with cirrhosis: Current role and novel perspectives. World J Gastroenterol 2022;28(33):4773-4786
25th	Neuro	Raman. A Brief Review of Bolus Osmotherapy Use for Managing Severe Traumatic Brain Injuries in the Pre-Hospital and Emergency Department Settings. Trauma Care 2022;2(3):427-433
24th	Respiratory	Bussini. Diagnosis, management and treatment of nosocomial pneumonia in ICU: a narrative review. J Emerg Crit Care Med 2022;epublished July 27th
23rd	Haematology	Mahečić. The Limits of Acute Anemia. J Clin Med 2022;11(18):5279
22nd	Circulatory	Koratala. Diagnosis of Fluid Overload: from Conventional to Contemporary Concepts. Cardiorenal Med 2022;epublished September 12th
21st	Nutrition	Dickerson. Obesity and critical care nutrition: current practice gaps and directions for future research. Crit Care 2022;26:283
20th	Gastrointestinal	Szatmary. Acute Pancreatitis: Diagnosis and Treatment. Drugs 2022;September 8th
19th	Gastrointestinal	Radonjić. Point-of-Care Abdominal Ultrasonography (POCUS) on the Way to the Right and Rapid Diagnosis. Diagnostics 2022;12(9):2052
18th	Respiratory	Sklar. Advances in Ventilator Management for Patients with Acute Respiratory Distress Syndrome. Clin Chest Med 2022;43(3):499-509
17th	Circulatory	Carbone. Septic Cardiomyopathy: From Pathophysiology to the Clinical Setting. Cells 2022;11(18):2833
16th	Neuro	Henke. Autonomic Dysfunction and Management after Spinal Cord Injury: A Narrative Review. J Pers Med 2022;12(7):1110
15th	Respiratory	Bos. Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes. Lancet 2022;epublished September 4th
14th	Gastrointestinal	Szatmary. Acute Pancreatitis: Diagnosis and Treatment. Drugs 2022;September 8th
13th	Respiratory	Gorman. Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management. Lancet 2022;epublished September 4th
12th	Circulatory	Miller. Fluid Volume Homeostasis in Heart Failure: A Tale of 2 Circulations. J Am Heart Assoc 2022;epublished September 8th
11th	Neuro	Konar. Intensive Care Unit Management of Traumatic Brain Injury Patients. Journal of Neurointensive Care 2022; 5(1):1-8
10th	COVID-19	Lê. Current Advances in Lung Ultrasound in COVID-19 Critically Ill Patients: A Narrative Review. J Clin Med 2022;11(17):5001
9th	Circulatory	Scheitz. Stroke–Heart Syndrome: Recent Advances and Challenges. J Am Heart Assoc 2022;0:e026528
8th	Respiratory	Wick. Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome. Lancet Respir Med 2022;epublished August 29th
7th	Toxicology	Wu. Progress in the management of acute colchicine poisoning in adults. Intern Emerg Med 2022;epublished August 26th
6th	Trauma	Starr. Platelet Transfusion for Trauma Resuscitation. Curr Trauma Rep 2022;8:147–159
5th	Renal	Levine. Prolonged Intermittent Kidney Replacement Therapy. Clin J Am Soc Nephrol 2022;epublished August 29th
4th	Respiratory	Wallace. Benefits and options for voice restoration in mechanically ventilated intensive care unit patients with a tracheostomy. J Intensive Care Soc 2022;epublished July 10th
3rd	Neuro	Schober. Antifibrinolytics in the treatment of traumatic brain injury. Curr Opin Anaesth 2022;35(5):583-592
2nd	Perioperative	Pirie. Current approaches to acute postoperative pain management after major abdominal surgery: a narrative review and future directions. Br J Anaesth 2022;129(3):378-393
1st	Renal	Achanti. Acid-Base Disorders in the Critically III Patient. Clin J Am Soc Nephrol 2022;epublished August 24th

September

30th	Sepsis	Giamarellou. Current and Potential Therapeutic Options for Infections Caused by Difficult-to-Treat and Pandrug Resistant Gram-Negative Bacteria in Critically Ill Patients. Antibiotics 2022;11(8):1009
29th	Haematology	Neef. Patient blood management in the ICU. A narrative review of the literature. Eur J Anaesthesiol Intensive Care Med 2022;epublished August 5th
28th	Circulatory	Talle. Cardiac Complications of Hypertensive Emergency: Classification, Diagnosis and Management Challenges. J Cardiovasc Dev Dis 2022;9:276
27th	Neuro	Pinto. Status epilepticus: review on diagnosis, monitoring and treatment. Arq Neuropsiquiatr 2022;80(5 Suppl 1):193-203
26th	Neuro	Rodriguez. Critical Illness Myopathy: Diagnostic Approach and Resulting Therapeutic Implications. Curr Treat Options Neurol 2022;24(4):173-182
25th	Neonatology	Thekkeveedu. Ventilation-Induced Lung Injury (VILI) in Neonates: Evidence-Based Concepts and Lung-Protective Strategies. J Clin Med 2022;11(3):557
24th	Neonatology	Coleman. Neonatal Acute Kidney Injury. Front Pediatr 2022;10:842544
23rd	Sepsis	Raabe. Lassa Virus Infection: a Summary for Clinicians. Int J Infect Dis 2022;119:187-200
22nd	Renal	Esson. Cutaneous manifestations of acute kidney injury. Clin Kid J 2022;15(5):855–864
21st	Respiratory	Brodie. ECMO During Respiratory Pandemics: Past, Present, and Future. Am J Respir Crit Care 2022;epublished February 24th
20th	Neuro	Lidington. Cerebral Autoregulation in Subarachnoid Hemorrhage. Front Neurol 2021;12:688362
19th	Airway	De Jong. How to improve intubation in the intensive care unit. Update on knowledge and devices. Intensive Care Med 2022;48:1287–1298
18th	Paediatrics	Volakli. High flow nasal cannula therapy in children: working principles and treatment failure predictors. Signa Vitae 2022;epublished May 11th
17th	Sepsis	Baracaldo-Santamaría. Therapeutic Drug Monitoring of Antifungal Agents in Critically Ill Patients: Is There a Need for Dose Optimisation? Antibiotics 2022;11(5):645
16th	Trauma	Girón-Arango. Is There a Role for Transesophageal Echocardiography in the Perioperative Trauma Patient?. Curr Anesthesiol Rep 2022;12:210–216
15th	Sepsis	Czeresnia. Strongyloides stercoralis. Lung 2022;200:141–148
14th	Respiratory	Bialka. Flow-controlled ventilation - a new and promising method of ventilation presented with a review of the literature. Anaesthesiol Intensive Ther 2022;epublished February 10th
13th	Neuro	Labak. Multimodality Monitoring for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage: A Mini Review. Front Neurol 2022;13:869107
12th	Circulatory	Mathew. Optimal Perfusion Targets in Cardiogenic Shock. JACC Adv 2022;1(2):1–14
11th	Renal	Molitoris. Low-Flow Acute Kidney Injury: The Pathophysiology of Prerenal Azotemia, Abdominal Compartment Syndrome, and Obstructive Uropathy. Clin J Am Soc Nephrol 2022;epublished May 18th
10th	Hepatobiliary	Baiges. Management of Liver Decompensation in Advanced Chronic Liver Disease: Ascites, Hyponatremia, and Gastroesophageal Variceal Bleeding. Clin Drug Investig 2022;epublished April 27th
9th	GI	Khanna. My Treatment Approach to Clostridioides difficile Infection. Mayo Clin Proc 2021;96(8):2192-2204
8th	Circulatory	Horejsek. Novel Methods for Predicting Fluid Responsiveness in Critically Ill Patients-A Narrative Review. Diagnostics 2022;12(2):513
7th	Neuro	Kvolik. Analgesia in the Neurosurgical Intensive Care Unit. Front Neurol 2022;12:819613
6th	COVID-19	Kethireddy. Challenges in hyperglycemia management in critically ill patients with COVID-19. World J Crit Care Med 2022;11(4):219-227
5th	Trauma	Starr. Platelet Transfusion for Trauma Resuscitation. Curr Trauma Rep 2022;8:147–159
4th	Respiratory	Ghazali. Interdisciplinary teamwork for chest tube insertion and management: an integrative review. Anaesthesiol Intensive Ther 2021;53(5):456–465
3rd	Toxicology	Fucili. Tips for avoiding common mistakes in out-of-hospital diagnosis of carbon monoxide poisoning. J Anesth Analg Crit Care 2022;2:14
2nd	Sepsis	Garber. Pneumonia Update for Emergency Clinicians. Curr Emerg Hosp Med Rep 2022;epublished July 20th
1st	Airway	Pasick. An Updated Review of Subglottic Stenosis: Etiology, Evaluation, and Management. Curr Pulmonol Rep 2022;11:29–38

August

31st	COVID-19	Short. Extracorporeal membrane oxygenation for coronavirus disease 2019-related acute respiratory distress syndrome. Curr Opin Crit Care 2022;28(1):90-97
30th	Neuro	Chung. Peri-operative neurological monitoring with electroencephalography and cerebral oximetry: a narrative review. Anaesthesia 2022;77(Suppl 1):113-122
29th	Respiratory	Conti. Evidence and Current Use of Levosimendan in the Treatment of Heart Failure: Filling the Gap. Drug Des Devel Ther 2021;15:3391-3409
28th	Hepatobiliary	Queck. Transplantation in Acute-on-Chronic Liver Failure: Feasibility and Futility. Clin Liver Dis 2022;19:191-193
27th	Nutrition	Duan. Nutritional support in the acute phase of critical illness—how to break the dilemma. Signa Vitae 2022;epublished March 31st
26th	Respiratory	Fortún. Diagnostic and therapeutic approach to fungal pneumonia in the critically ill patient. Rev Esp Quimioter 2022;35(Suppl. 1):97-103
25th	Neuro	Robba. Acute ischaemic stroke and its challenges for the intensivist. European Heart Journal. Acute Cardiovascular Care 2022;epublished February 3rd
24th	COVID-19	Gao. Application of POCUS in patients with COVID-19 for acute respiratory distress syndrome management: a narrative review. BMC Pulm Med 2022;22:52
23rd	Airway	Mohamed. Airway Management During Cardiopulmonary Resuscitation. Curr Anesthesiol Rep 2022;epublished March 25th
22nd	Respiratory	Leidi. Risk Stratification in Patients with Acute Pulmonary Embolism: Current Evidence and Perspectives. J Clin Med 2022;11(9):2533
21st	Hepatobiliary	Kaur. Pretransplant management of the patient with severe acute-on-chronic liver failure. Clin Liver Dis 2022;19:187–190
20th	Renal	Pliquett. Cardiorenal Syndrome: An Updated Classification Based on Clinical Hallmarks. J Clin Med 2022;11(10):2896
19th	Sepsis	Bauer. The liver-gut-axis: initiator and responder to sepsis. Curr Opin Crit Care 2022;28(2):216-220
18th	Rheumatology	Satpanich. Gout ﬂare in the critical care setting: diagnostic challenges and treatment options. Signa Vitae 2022 18(3);9-17
17th	Oncology	Lupușoru. Tumor Lysis Syndrome: An Endless Challenge in Onco-Nephrology. Biomedicines 2022;10(5):1012
16th	Paediatrics	Bartlett. Pediatric Acute Liver Failure: Re-examining key clinical features, current management, and research prospects. Liver Transpl 2022;epublished May 12th
15th	Immunology	Whyte. Emergency treatment of anaphylaxis: concise clinical guidance. Clin Med 2022;22:332-339
14th	Circulatory	Zhou. Bridge to transplantation from mechanical circulatory support: a narrative review. J Thorac Dis 2021;13(12):6911-6923
13th	Sepsis	Losito. New Drugs for the Treatment of Pseudomonas aeruginosa Infections with Limited Treatment Options: A Narrative Review. Antibiotics 2022;11(5):579
12th	Renal	Silva. Kidney metabolism and acid–base control: back to the basics. Pflugers Arch - Eur J Physiol 2022;epublished May 5th
11th	Hepatobiliary	Rodge. Management of Refractory Variceal Bleed in Cirrhosis. J Clin Exp Hepatol 2022;12(2):595-602
10th	Respiratory	Huang. Advances in medical imaging to evaluate acute respiratory distress syndrome. Chin J Acad Radiol 2021;epublished July 17th
9th	Airway	Hyman. Awake Intubation Techniques, and Why It Is Still an Important Skill to Master. Curr Anesthesiol Rep 2022;epublished March 30th
8th	Neuro	Imran. Acute Reperfusion Therapies for Acute Ischemic Stroke. J Clin Med 2021;10(16):3677
7th	Neuro	Boelens. Poor physical recovery after critical illness: incidence, features, risk factors, pathophysiology, and evidence-based therapies. Curr Opin Crit Care 2022;28(4):409-416
6th	Haematology	Heubner. Point of care coagulation management in anesthesiology and critical care. Minerva Anestesiologica 2022;88(7-8):615-28
5th	Renal	Lindner. Hyponatremia in the emergency department. Am J Emerg Med 2022;60:1-8
4th	Respiratory	Bitker. Imaging the acute respiratory distress syndrome: past, present and future. Intensive Care Med 2022;epublished July 14th
3rd	Circulatory	Meuwese. The ABCDE approach to difficult weaning from venoarterial extracorporeal membrane oxygenation. Crit Care 2022;26:216
2nd	Neuro	Hawryluk. Intracranial pressure: current perspectives on physiology and monitoring. Intensive Care Med 2022;epublished July 11th
1st	COVID-19	Smith. Managing Severe Hypoxic Respiratory Failure in COVID-19. Curr Emerg Hosp Med Rep 2022;epublished May 11th

July

31st	Hepatobiliary	Pan. Acute Liver Failure Management and Liver Transplantation. Liver Transpl 2022;epublished May 16th
30th	Endocrine	Téblick. Critical Illness–induced Corticosteroid Insufficiency: What It Is Not and What It Could Be, J Clin Endocrinol Metab 2022;107(7):2057–2064
29th	Paediatrics	Bertazza Partigiani. Management of Hypertensive Crises in Children: A Review of the Recent Literature. Front Pediatr 2022;10:880678
28th	Trauma	Hanna. The Use of Whole Blood Transfusion in Trauma. Curr Anesthesiol Rep 2022;12:234–239
27th	Sepsis	Szychowiak. Inhaled antibiotics in critical care: state of the art and future perspectives. Infect Dis Now 2022;epublished May 7th
26th	Haematology	Ackfeld. Blood Transfusion Reactions-A Comprehensive Review of the Literature including a Swiss Perspective. J Clin Med 2022;11(10):2859
25th	Renal	Braet. Treatment of acute kidney injury in cancer patients. Clin Kid J 2022;15(5):873–884
24th	Hepatobiliary	Velasco. Evaluation and management of emergencies in the patient with cirrhosis. Rev Gastroenterol Mex 2022;epublished May 12th
23rd	Gastrointestinal	Long. Pain and its management in severe acute pancreatitis. J Transl Crit Care Med 2022;4:9
22nd	Respiratory	Bajaj. Foreign body aspiration. J Thorac Dis 2021;13(8):5159-5175
21st	Airway	Bombeek. What is new in airway management. J Clin Monit Comput 2022;36:301–304
20th	COVID-19	Fumagalli. Ventilator-associated pneumonia among SARS-CoV-2 acute respiratory distress syndrome patients. Curr Opin Crit Care 2022;28(1):74–82
19th	Resuscitation	Richter. Cerebral oxygenation monitoring in patients during and after cardiac arrest -- a narrative review of current methods and evidence. Signa Vitae 2021;17(6):18-24
18th	Circulatory	Møller. Impella to Treat Acute Myocardial Infarct-Related Cardiogenic Shock. J Clin Med 2022;11(9):2427
17th	Neuro	Vaišvilas. Paraneoplastic encephalitis: clinically based approach on diagnosis and management. Postgraduate Med J 2022;epublished May 19th
16th	Ethics	Michalowski. DNACPR Decisions: Aligning Law, Guidance, and Practice. Medical Law Review 2022;epublished April 29th
15th	Miscellaneous	Ronco. Hemoperfusion: technical aspects and state of the art. Crit Care 2022;26(1):135
14th	Perioperative	Ludbrook. The Hidden Pandemic: the Cost of Postoperative Complications. Curr Anesthesiol Rep 2022;12:1–9
13th	Paediatrics	Turcotte. Pediatric Intestinal Pseudo-Obstruction: Progress and Challenges. Front Pediatr 2022;10:837462
12th	Trauma	Pape. Pathophysiology in patients with polytrauma. Injury 2022;epublished May 14th
11th	Sepsis	Evers. Potential pandemic pathogens series: Nipah virus. Neth J Crit Care May 2022;30(3):94-98
10th	Trauma	Heinz. Point-of-Care Ultrasound for the Trauma Anesthesiologist. Curr Anesthesiol Rep 2022;12:217–225
9th	Renal	Colliou. Kidney Failure after Liver Transplantation. Transplantology 2021;2:315–335
8th	Airway	Boutros. Multidisciplinary management of tracheobronchial injury. Eur Respir Rev 2022;31(163):210126
7th	COVID-19	Di Meglio. Chest imaging in patients with acute respiratory failure because of coronavirus disease 2019. Curr Opin Crit Care 2022;28(1):17–24
6th	Neuro	Stollings. Delirium in critical illness: clinical manifestations, outcomes, and management. Intensive Care Med 2021;epublished August 16th
5th	Circulatory	Monnet. Prediction of fluid responsiveness. What's new? Ann Intensive Care 2022;12(1):46
4th	Resuscitation	Markota. Temperature management and its role in cardiac arrest patients—a review. Signa Vitae 2022;18(3):1-8
3rd	Airway	Thota. Airway management in patients with obesity. Saudi J Anaesth 2022;16:76-81
2nd	Trauma	Smith. Narrative review of vascular iatrogenic trauma and endovascular treatment. Ann Transl Med 2021;9(14):1199
1st	Sepsis	Zhang. Blood purification for sepsis: an overview. Precis Clin Med 2021;4(1):45–55

June

30th	Paediatrics	Bartlett. Pediatric Acute Liver Failure: Re-examining key clinical features, current management, and research prospects. Liver Transpl 2022;epublished May 12th
29th	Monitoring	Bockholt. Real-Time Monitoring of Blood Parameters in the Intensive Care Unit: State-of-the-Art and Perspectives. J Clin Med 2022;11(9):2408
28th	Circulatory	Balahura. The Management of Hypertensive Emergencies—Is There a “Magical” Prescription for All? J Clin Med 2022;11(11):3138
27th	Respiratory	Bos. Towards a biological definition of ARDS: are treatable traits the solution?. ICMx 2022;10:8
26th	Haematology	Palmer. How to approach haemolysis: Haemolytic anaemia for the general physician. Clin Med 2022;22:210-213
25th	Haematology	Ashworth. Thrombocytopenia: the good, the bad and the ugly. Clin Med 2022;22:214-217
24th	Sepsis	Patel. Sepsis Management for the Nephrologist. Clin J Am Soc Nephrol 2022;epublished May 12th
23rd	Sepsis	Li. Current Understanding of Long-Term Cognitive Impairment After Sepsis. Front Immunol 2022;13:855006
22nd	Paediatrics	Engel. Modified ABCDEF-Bundles for Critically Ill Pediatric Patients - What Could They Look Like? Front Pediatr 2022;10:886334
21st	Peroperative	Guarracino. Perioperative hypotension: causes and remedies. J Anesth Analg Crit Care 2022;2:17
13th	Neuro	Meyfroidt. Management of moderate to severe traumatic brain injury: an update for the intensivist. Intensive Care Med 2022;epublished May 20th
12th	COVID-19	Chen. Review of Anti-inflammatory and Antiviral Therapeutics for Hospitalized Patients Infected with Severe Acute Respiratory Syndrome Coronavirus 2. Crit Care Clin 2022;38(3):587-600
11th	COVID-19	Blatz. Severe COVID-19 and Multisystem Inflammatory Syndrome in Children in Children and Adolescents. Crit Care Clin 2022;38(3):571-586
10th	COVID-19	Tisminetzky. Extracorporeal Membrane Oxygenation in COVID-19. Crit Care Clin 2022;38(3):535-552
9th	COVID-19	Empson. COVID-19 Acute Respiratory Distress Syndrome. One Pathogen, Multiple Phenotypes. Crit Care Clin 2022;38(3):505-519
8th	COVID-19	Gibbs. Role of Acute Thrombosis in Coronavirus Disease 2019. Crit Care Clin 2022;38(3):491-504
7th	COVID-19	Levitus. COVID-19 in the Critically Ill Pregnant Patient. Crit Care Clin 2022;38(3):521-534
6th	COVID-19	Shankar. A Clinical Update on Vasoactive Medication in the Management of Cardiogenic Shock. Clinical Medicine Insights: Cardiology 2022;16:1-11
5th	Miscellaneous	Bjorklund. Pediatric Critical Care in Resource Limited Settings—Lessening the Gap Through Ongoing Collaboration, Advancement in Research and Technological Innovations. Front Pediatr 2022;9:791255
4th	Trauma	McCoy. Back to the Future: Whole Blood Resuscitation of the Severely Injured Trauma Patient. Shock 2021;56(1S):9-15
3rd	Sepsis	Bauer. Towards an ecological definition of sepsis: a viewpoint. Intensive Care Med Exp 2021;9:63
2nd	Respiratory	Roca. To prone or not to prone ARDS patients on ECMO. Crit Care 2021;25:315
1st	COVID-19	Menga. Noninvasive respiratory support for acute respiratory failure due to COVID-19. Curr Opin Crit Care 2022;28(1):25–50

May

31st	Circulatory	Lampejo. Acute myocarditis: aetiology, diagnosis and management. Clin Med 2021;21(5):e505-e510
30th	Neuro	Chacón-Aponte. Brain-lung interaction: a vicious cycle in traumatic brain injury. Acute Crit Care 2022;epublished February 11th
29th	Respiratory	Redaelli. Nitric oxide: Clinical applications in critically ill patients. Nitric Oxide 2022;epublished February 2nd
28th	Trauma	Brill. The Role of TEG and ROTEM in Damage Control Resuscitation. Shock 2021;56(1S):52-61
27th	Sepsis	Kunz Coyne. Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa. Infect Dis Ther 2022;epublished February 12th
26th	Endocrine	Noetzlin. Short-term glucocorticoid-related side effects and adverse reactions: a narrative review and practical approach. Swiss Med Wkly 2022;152:w30088
25th	Respiratory	Ghattas. State of the art: percutaneous tracheostomy in the intensive care unit. J Thorac Dis 2021;13(8):5261-5276
24th	Neuro	Anderson. Electroencephalogram patterns in critical care: A primer for acute care doctors. JICS 2022;23(1):58-69
23rd	Circulatory	Flick. What is new in hemodynamic monitoring and management?. J Clin Monit Comput 2022;36:305–313
22nd	Burns	McCann. Major burns: Part 1. Epidemiology, pathophysiology and initial management. BJA Education 2022;22(3):94-103
21st	Paediatrics	Gialamprinou. Neonatal Sepsis and Hemostasis. Diagnostics 2022;12(2):261
20th	Sepsis	Sweeney. Integrated Multiorgan Bedside Ultrasound for the Diagnosis and Management of Sepsis and Septic Shock. Semin Respir Crit Care Med 2021;42(05):641-649
19th	Renal	Li. Contrast-Associated Acute Kidney Injury: Advances and Challenges. Int J Gen Med 2022;15:1537-1546
18th	Respiratory	Kurman. Persistent air leak management in critically ill patients. J Thorac Dis 2021;13(8):5223-5231
17th	Circulatory	Kunkel. 2021 Update for the Diagnosis and Management of Acute Coronary Syndromes for the Perioperative Clinician. J Cardiothorac Vasc Anesth 2021;epublished July 22nd
16th	Neuro	Baggiani. Acute traumatic brain injury in frail patients - the next pandemic. Curr Opin in Crit Care 2022;28(2):166-175
15th	Sepsis	Ivanov. Emerging Antifungal Targets and Strategies. Int J Mol Sci 2022;23(5):2756
14th	Renal	Kan. Vancomycin-Associated Acute Kidney Injury: A Narrative Review from Pathophysiology to Clinical Application. Int J Mol Sci 2022;;23(4):2052
13th	Respiratory	Pearson. Management of Respiratory Failure. Ventilator Management 101 and Noninvasive Ventilation. CJASN 2022;17(4):572-580
12th	COVID-19	Camporota. Pathophysiology of coronavirus-19 disease acute lung injury. Curr Opin Crit Care 2022;28(1):9–16
11th	Resuscitation	Suverein. Ethics of ECPR Research. Resuscitation 2021;epublished August 16th
10th	Neuro	Evered. Acute peri-operative neurocognitive disorders: a narrative review. Anaesthesia 2022;77(Suppl 1):34-42
9th	Circulatory	Femia. Right ventricular myocardial infarction: pathophysiology, clinical implications and management. Rev Cardiovasc Med 2021;22(4):1229-1240
8th	Renal	Platt. Literature review of the mechanisms of acute kidney injury secondary to acute liver injury. World J Nephrol 2022;11(1):13-29
7th	Sepsis	Śmiechowicz. The Rationale and Current Status of Endotoxin Adsorption in the Treatment of Septic Shock. J Clin Med 2022;11(3):619
6th	Paediatrics	Tzimenatos. Managing Diabetic Ketoacidosis in Children. Ann Emerg Med 2021;78(3):340-3
5th	Statistics	Introna. Bayesian statistics in anesthesia practice: a tutorial for anesthesiologists. J Anesth 2022;epublished February 11th
4th	Imaging	Lau. Point-of-care ultrasound for critically-ill patients: A mini-review of key diagnostic features and protocols. World J Crit Care Med 2022;11(2):70-84
3rd	Trauma	Ramanathan. Coagulopathy related to trauma: Is it time for a goal-directed approach? Ann Acad Med Singap 2022;51(1):5-7
2nd	Sepsis	Ruiz-Rodriguez. Precision medicine in sepsis and septic shock: From omics to clinical tools. World J Crit Care Med 2022;11(1):1-21
1st	Nutrition	Lier. Emergency Blood Transfusion for Trauma and Perioperative Resuscitation: Standard of Care. Transfus Med Hemother 2021;48(6):366-376

April

30th	Renal	Foti. Acute Kidney Injury and Extracorporeal Membrane Oxygenation: Review on Multiple Organ Support Options, Int J Nephrol Renovasc Dis 2021;14:321-329
29th	Hepatobiliary	Laique. Surgical Considerations Regarding Transplantation for the Patient With Acute-on-Chronic Liver Failure. Clin Liver Dis 2022;epublished January 28th
28th	Respiratory	Patolia. Bronchoscopy in intubated and non-intubated intensive care unit patients with respiratory failure. J Thorac Dis 2021;13(8):5125-5134
27th	Resuscitation	Mazzoli. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Non-Traumatic Cardiac Arrest: A Narrative Review of Known and Potential Physiological Effects. J Clin Med 2022;11(3):742
26th	Neuro	Tarwade. Endotracheal intubation sedation in the intensive care unit. World J Crit Care Med 2022;11(1):33-39
25th	Circulatory	Patel. Futility in Transcatheter Aortic Valve Implantation: A Search for Clarity. Interventional Cardiology 2022;17:e01
24th	Trauma	Khorram-Manesh. Review of Military Casualties in Modern Conflicts—The Re-emergence of Casualties From Armored Warfare. Military Medicine 2022;187(3-4):e313–e321
23rd	Sepsis	Lescroart. Beta-blockers in septic shock: What is new? J Intensive Med 2022;epublished April 3rd
22nd	Perioperative	Hullin. Cardiac Surgery in Advanced Heart Failure. J Clin Med 2022;11(3):773
21st	Obstetrics	Mohan. Metabolic emergencies in pregnancy. Clin Med 2021;21(5):e438-e440
20th	Respiratory	Van Slambrouck. A Focused Review on Primary Graft Dysfunction after Clinical Lung Transplantation: A Multilevel Syndrome. Cells 2022;11(4):745
19th	Toxicology	Chen. The Role of Angiotensin II in Poisoning-Induced Shock—a Review. J Med Toxicol 2022;18:145–154
18th	Circulatory	Flick. What is new in hemodynamic monitoring and management? J Clin Monit Comput 2022;epublished April 8th
17th	Renal	Colliou. Kidney Failure after Liver Transplantation. Transplantology 2021;2:315–335
16th	Gastrointestinal	Stojek. Gastroparesis in the intensive care unit. Anaesthesiol Intensive Ther 2021;53(5):450–455
15th	Respiratory	Thakore. Medical thoracoscopy in intensive care unit. J Thorac Dis 2021;13(8):5232-5241
14th	Resuscitation	Skrifvars. Monitoring and modifying brain oxygenation in patients at risk of hypoxic ischaemic brain injury after cardiac arrest. Crit Care 2021;25:312
13th	Circulatory	Park. Myocardial injury in noncardiac surgery. Korean J Anesthesiol 2022;75(1):4-11
12th	COVID-19	Long. Clinical update on COVID-19 for the emergency and critical care clinician: Medical management. Am J Emerg Med 2022;56:158-170
11th	Resuscitation	Bronder. Revisiting EEG as part of the multidisciplinary approach to post-cardiac arrest care and prognostication: A review. Resuscitation Plus 2022;9:100189
10th	Trauma	Gauss. Massive transfusion in trauma: an evolving paradigm. Minerva Anestesiologica 2022;88(3):184-91
9th	Paediatrics	Kollisch-Singule. Mechanical Ventilation in Pediatric and Neonatal Patients. Front Physiol 2022;epublished March 17th
8th	Renal	Velez. Hepatorenal Syndrome Type 1: From Diagnosis Ascertainment to Goal-Oriented Pharmacologic Therapy. Kidney360 2022;3(2):382–395
7th	Respiratory	Goetz. Mucus Clearance Strategies in Mechanically Ventilated Patients. Front Physiol 2022;13:834716
6th	Endocrine	Alhatemi. Glycemic control in the critically ill: Less is more. Cleve Clin J Med 2022;89(4):191-199
5th	Respiratory	Cheng. Does airway pressure release ventilation offer new hope for treating acute respiratory distress syndrome? J Intensive Med 2022;epublished March 28th
4th	Circulatory	Bergmark. Acute coronary syndromes. Lancet 2022;399(10332):1347-1358
3rd	Haematology	Nath. Clinical application of viscoelastic point-of-care tests of coagulation-shifting paradigms. Ann Card Anaesth 2022;25:1-10
2nd	Respiratory	Liaqat. Evidence-Based Mechanical Ventilatory Strategies in ARDS. J Clin Med 2022;11(2):319
1st	Nutrition	Berger. When is parenteral nutrition indicated? J Intensive Med 2022;epublished January 10th

March

31st	Neuro	Milne. Neuromonitoring and Neurocognitive Outcomes in Cardiac Surgery: A Narrative Review. J Cardiothorac Vasc Anesth 2021;epublished July 20th
30th	Sepsis	Slavin. When to change treatment of acute invasive aspergillosis: an expert viewpoint. J Antimicrobial Chemotherapy 2022;77(1):16–23
29th	Renal	Ostermann. Acute kidney injury in ECMO patients. Crit Care 2021;25:313
28th	Sepsis	Boissier. Septic cardiomyopathy: Diagnosis and management. J Intensive Med 2021;epublished December 27th
27th	COVID-19	Kharat. Prone position in COVID 19-associated acute respiratory failure. Curr Opin Crit Care 2022;28(1):57–65
26th	Resuscitation	Rea. Out of hospital cardiac arrest: Past, present, and future. Resuscitation 2021;165:101-109
25th	Haematology	Iba. Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia. Crit Care Med. 2022;50(1):e80–e86
24th	Respiratory	Hu. Management of complex pleural disease in the critically ill patient. J Thorac Dis 2021;13(8):5205-5222
23rd	Perioperative	Perchermeier. The Use of Corticosteroids for Cardiopulmonary Bypass in Adults. Curr Anesthesiol Rep 2021;11:292–297
22nd	Perioperative	Labus. Role of Echocardiography for the Perioperative Assessment of the Right Ventricle. Curr Anesthesiol Rep 2022;11:306–317
21st	Haematology	Fodil. Severe Thrombotic Thrombocytopenic Purpura (TTP) with Organ Failure in Critically Ill Patients. J Clin Med 2022;11(4):1103
20th	Circulatory	Meani. ECPella: Concept, Physiology and Clinical Applications. J Cardiothorac Vasc Anesth 2022;36(2):557-566
19th	Neuro	Wiles. Management of traumatic brain injury: a narrative review of current evidence. Anaesthesia 2022;77(Suppl 1):102-112
18th	Sepsis	Barichello. Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review. Crit Care 2022;26:14
17th	Circulatory	Wang. Resuscitation fluids as drugs: targeting the endothelial glycocalyx. Chin Med J 2022;epublished January 4th
16th	Respiratory	Lee. Fluid Therapy and Acute Respiratory Distress Syndrome. Crit Care Clin 2021;37(4):867-875
15th	Sepsis	Donovan. Adjunctive treatments for the management of septic shock – a narrative review of the current evidence. Anaesthesia 2021;76(9):1245-1258
14th	Gastrointestinal	Wei. An overview of percutaneous endoscopic gastrostomy tube placement in the intensive care unit. J Thorac Dis 2021;13(8):5277-5296
13th	Circulatory	Hsu. Hemodynamics for the Heart Failure Clinician: A State-of-the-Art Review. J Card Fail 2021;epublished August 10th
12th	Sepsis	Niederman. Initial antimicrobial management of sepsis. Crit Care 2021;25(1):307
11th	Respiratory	Marini. Improving lung compliance by external compression of the chest wall. Crit Care 2021;25:264
10th	Obstetrics	Lim. Liver diseases in pregnancy. Clin Med 2021;21(5):e441-e445
9th	Renal	Bouajram. A Clinician’s Guide to Dosing Analgesics, Anticonvulsants, and Psychotropic Medications in Continuous Renal Replacement Therapy. Kidney Int Rep 2021;6(8):2033-2048
8th	Resuscitation	Abrams. Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications. Intensive Care Med 2021;epublished September 10th
7th	Respiratory	Charya. Management of life-threatening hemoptysis in the ICU. J Thorac Dis 2021;13(8):5139-5158
6th	Trauma	Cretcher. Splenic trauma: endovascular treatment approach. Ann Transl Med 2021;9(14):1194
5th	Trauma	Weir. Endovascular management of pelvic trauma. Ann Transl Med 2021;9(14):1196
4th	Trauma	Roberts. Hepatic trauma. Ann Transl Med 2021;9(14):1195
3rd	Trauma	Brown. Acute traumatic injury of the aorta: presentation, diagnosis, and treatment. Ann Transl Med 2021;9(14):1193
2nd	Trauma	Roberts. Hepatic trauma. Ann Transl Med 2021;9(14):1195
1st	Trauma	Weir. Endovascular management of pelvic trauma. Ann Transl Med 2021;9(14):1196

February

28th	Trauma	Khurana. Endovascular interventions in the management of acute extremity trauma: a narrative review. Ann Transl Med 2021;9(14):1197
27th	Neuro	Imran. Acute Reperfusion Therapies for Acute Ischemic Stroke. J Clin Med 2021;10(16):3677
26th	Trauma	Jamal. Emerging approaches to pre-hospital hemorrhage control: a narrative review. Ann Transl Med 2021;9(14):1192
25th	Circulatory	Randhawa. A Pragmatic Approach to Weaning Temporary Mechanical Circulatory Support: A State-of-the-Art Review. JACC Heart Fail 2021;epublished August 5th
24th	Sepsis	Yoon. MALDI-TOF Mass Spectrometry Technology as a Tool for the Rapid Diagnosis of Antimicrobial Resistance in Bacteria. Antibiotics 2021;10(8):982
23rd	Respiratory	Tilea. Critical Care Management of Decompensated Right Heart Failure in Pulmonary Arterial Hypertension Patients – An Ongoing Approach. The Journal of Critical Care Medicine 2020;7(3):170-183
22nd	Resuscitation	Gijtenbeek. POCUS series: ultrasound during cardiopulmonary resuscitation. Neth J Crit Care 2021;29(4):170-175
21st	Renal	Pesonen. Acute kidney injury after brain injury: does it exist? Minerva Anestesiologica 2021;87(7):823-7
20th	Hepatology	Matar. Extracorporeal Liver Support: A Bridge to Somewhere. Clin Liver Dis 2021;epublished July 22nd
19th	Renal	Singh. Acute Kidney Injury in Cardiogenic Shock: An Updated Narrative Review. J Cardiovasc Dev Dis 2021;8(8):88
18th	Respiratory	Weinstein. Advanced management of intermediate-high risk pulmonary embolism. Crit Care 2021;25:311
17th	Circulatory	Cook. Assessment and management of cardiovascular disease in the intensive care unit. Heart 2021;epublished June 24th
16th	Sepsis	Grasselli. Secondary infections in critically ill patients with COVID-19. Crit Care 2021;25:317
15th	Circulatory	Heringlake. Still a place for aortic counterpulsation in cardiac surgery and patients with cardiogenic shock?. Crit Care 2021;25:309
14th	Metabolic	Yagi. Management of acute metabolic acidosis in the ICU: sodium bicarbonate and renal replacement therapy. Crit Care 2021;25:314
13th	Metabolic	Wiles. Severe hypertension in pregnancy. Clin Med 2021;21(5):e451-e456
12th	Hepatobiliary	Zanetto. Recent Advances in the Management of Acute Variceal Hemorrhage. J Clin Med 2021;10(17):3818
11th	Respiratory	Thachuthara-George. Pneumothorax in patients with respiratory failure in ICU. J Thorac Dis 2021;13(8):5195-5204
10th	Resuscitation	Abrams. Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications. Intensive Care Med 2021;48:1-15
9th	Neuro	Bowman. Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression. Crit Care 2021;25(1):334
8th	Hepatology	Gougol. Alcoholic Hepatitis. Clin Liver Dis 2021;18(2):90-95
7th	Respiratory	Coleman. Acute Respiratory Distress Syndrome. Ventilator Management and Rescue Therapies. Crit Care Clin 2021;37(4):851-866
6th	Sepsis	Ladzinski. Rational Fluid Resuscitation in Sepsis for the Hospitalist. A Narrative Review. Mayo Clin Proc 2021;96(9):2464-2473
5th	Dermatology	Bromley. Life-threatening skin conditions presenting to critical care. Br J Anaesth 2021;21(10):376-383
4th	Resuscitation	Lim. Extracorporeal life support in adult patients with out-of-hospital cardiac arrest. Singapore Med J 2021;62(8):433-437
3rd	Respiratory	Raghu. Cryptogenic organising pneumonia: current understanding of an enigmatic lung disease. Eur Respir Rev 2021 30:210094
2nd	Liver	Tandon. Artificial liver support systems. J Gastroenterol Hepatol 2021;36(5):1164-1179
1st	Oncology	Shimabukuro-Vornhagen. Critical care management of chimeric antigen receptor T-cell therapy recipients. CA Cancer J Clin 2021;epublished October 6th

January

31st	Geriatrics	Geen. Optimizing care for critically ill older adults. CMAJ 2021;193(39):E1525-E1533
30th	Respiratory	Winning. Oral health care for the critically ill: a narrative review. Crit Care 2021;25:353
29th	Circulatory	Notarianni. Mechanical Cardiac Circulatory Support: an Overview of the Challenges for the Anesthetist. Curr Anesthesiol Rep 2021;epublished October 1st
28th	Circulatory	Zhang. Narrative Review of Neurologic Complications in Adults on ECMO: Prevalence, Risks, Outcomes, and Prevention Strategies. Front Med 2021;8:713333
27th	Neuro	Poulsen. Delirium in Intensive Care. Curr Anesthesiol Rep 2021;epublished September 3rd
26th	COVID-19	Poor. Pulmonary Thrombosis and Thromboembolism in COVID-19. Chest 2021;160(4):1471-1480
25th	Trauma	Fecher. The Pathophysiology and Management of Hemorrhagic Shock in the Polytrauma Patient. J Clin Med 2021;10(20):4793
24th	Sepsis	Feng. Blood purification in sepsis and systemic inflammation. Curr Opin Crit Care 2021;epublished September 27th
23rd	Airway	Saini. Airway management in maxillofacial trauma. J Anaesthesiol Clin Pharm 2021;37(3):319-327
22nd	Neuro	Rossetti. What’s new on EEG monitoring in the ICU. Minerva Anestesiologica 2021;87(10):1139-45
21st	COVID-19	Gattinoni. COVID-19 pneumonia: pathophysiology and management. Eur Respir Rev 2021;30:210138
20th	Sepsis	Kollef. Timing of antibiotic therapy in the ICU. Crit Care 2021;25:360
19th	Renal	Verma. Prescribing Continuous Kidney Replacement Therapy in Acute Kidney Injury: A Narrative Review. Kidney Med 2021;3(5):827-836
18th	Sepsis	Duncan. Diagnostic Challenges in Sepsis. Curr Infect Dis Rep 2021;23:22
17th	Resuscitation	Sandroni. Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis. Intensive Care Med 2021;epublished October 27th
16th	Paediatrics	Berisha. Management of the Unexpected Difficult Airway in Neonatal Resuscitation. Front Pediatr 2021;9:699159
15th	Obstetrics	Erez. DIC in Pregnancy – Pathophysiology, Clinical Characteristics, Diagnostic Scores, and Treatments. J Blood Med 2022;13:21-44
14th	Endocrine	See. Glycemic targets in critically ill adults: A mini-review. World J Diabetes 2021 Oct;12(10):1719-1730
13th	Respiratory	Charokopos. Acute exacerbation of interstitial lung disease in the intensive care unit. World J Crit Care Med 2022;11(1):22-32
12th	Respiratory	Lagier. Perioperative Pulmonary Atelectasis: Part II. Clinical Implications. Anesthesiology 2022;136:206–236
11th	Neuro	Migdady. Management of status epilepticus: a narrative review. Anaesthesia 2022;77(Suppl 1):78-91
10th	Neuro	Demel. Reflection on the Past, Present, and Future of Thrombolytic Therapy for Acute Ischemic Stroke. Neurology 2021;97(20 Supplement 2):S170-S177
9th	Circulatory	Mielnicki. A systematic approach to transoesophageal echocardiography in the intensive care unit – a practical guide for intensivists. Anaesthesiol Intensive Ther 2021;53(3): 329–335
8th	Circulatory	Meng. Heterogeneous impact of hypotension on organ perfusion and outcomes: a narrative review. Br J Anaesth 2021;127(6):845-861
7th	Haematology	Neuenfeldt. Coagulopathies in Intensive Care Medicine: Balancing Act between Thrombosis and Bleeding. J Clin Med 2021;10(22):5369
6th	Respiratory	Park. High-flow nasal cannula for respiratory failure in adult patients. Acute Crit Care 2021;36(4):275-285
5th	Circulatory	Ávila-Reyes. Point-of-care ultrasound in cardiorespiratory arrest (POCUS-CA): narrative review article. Ultrasound J 2021;13:46
4th	Circulatory	Boissier. Septic cardiomyopathy: Diagnosis and management. J Intensive Med 2021;epublished December 27th
3rd	Neuro	Robba. Tier-three therapies for refractory intracranial hypertension in adult head trauma. Minerva Anestesiologica 2021;87(12):1359-66
2nd	Liver	Liu. Hepatorenal syndrome in acute-on-chronic liver failure with acute kidney injury: more questions requiring discussion. Gastroenterol Rep 2021;9(6):505–520
1st	Nutrition	Al-Dorzi. Nutrition support for critically ill patients. JPEN J Parenter Enteral Nutr 2021;45:S47–S59

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