Antibacterial Drugs

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Narrative Reviews

Antibacterial Drugs

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Major Sepsis Trials | Major Sepsis Guidelines

Sections

General | Monitoring & Investigations | Therapies

General

General

Cusack. Practical Lessons on Antimicrobial Therapy for Critically Ill Patients. Antibiotics 2024;13:162
Premachandra. Antibiotics in anesthesia and critical care. Ann Translational Med 2024;12(1):6

Japanese Practice

Seki. Optimizing antimicrobial use in Japan: strategies for dosage, combination therapy, de-escalation, oral switching, duration, and guideline adherence. Clin Pharmacol 2025;17:227-233

Background

Pathophysiology

Conditions

End-of-Life

Karlin. State-of-the-Art Review: Use of Antimicrobials at the End of Life. Clin Infect Dis 2024;78(3):e27–e36

Complications

General

Roger. Beta-Lactams Toxicity in the Intensive Care Unit: An Underestimated Collateral Damage? Microorganisms 2021;9:1505

Acute Kidney Injury

Monitoring & Investigations

Pharmacokinetics

Roger. Understanding antimicrobial pharmacokinetics in critically ill patients to optimize antimicrobial therapy: A narrative review. J Intensive Med. 2024;4(3):287-298.

Therapies

Aminoglycosides

Thy. Aminoglycosides for the Treatment of Severe Infection Due to Resistant Gram-Negative Pathogens. Antibiotics (Basel) 2023;12(5):860

Carbapenems

Gardner. Carbapenem de-escalation as an antimicrobial stewardship strategy: a narrative review. JAC Antimicrob Resist 2025;7(2):dlaf022

Emerging Therapies

Hickson. Emerging antimicrobial therapies for Gram-negative infections in human clinical use. NPJ Antimicrob Resist 2025;3:16

Fluoroquinolones

Rodrigues. The Rise, Fall, and Rethink of (Fluoro)quinolones: A Quick Rundown. Pathogens 2025;14(6):525

Last updated July 22nd, 2026