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Critical Care Reviews Newsletter
Newsletter 583 | February 12th, 2023
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The Trials to be Presented at CCR23 Are Now Being Announced
Welcome to the 583rd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials comparing methylprednisolone with intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 & closed with open endotracheal tube suction in mechanically ventilated neonates; systematic reviews and meta analyses on brain tissue oxygenation monitoring in subarachnoid hemorrhage for the detection of delayed ischemia & the association between hypocholesterolemia and mortality in critically ill patients with sepsis; and observational studies on hospital-acquired bloodstream infections in intensive care unit patients & prehospital ultrasound in undifferentiated dyspnea.
There are also guidelines on acute mechanical circulatory support & pediatric coma and disorders of consciousness; narrative reviews on advanced point-of-care bedside monitoring for acute respiratory failure & sequential extracorporeal therapy in sepsis; editorials on early mobilization in the ICU & methylprednisolone for heart surgery in infants; and commentaries on the uncertain future of the determination of brain death & the top 10 papers in acute cardiac care and ischaemic heart disease in 2022.
If you only have time to read one review article this week, try this one on selective prehospital advanced resuscitative care to prevent prehospital deaths from noncompressible torso hemorrhage.
CCR23
We've started to announce the trials to be presented at the Critical Care Reviews Meeting 2023, in Titanic Belfast. Our first trial is the long anticipated CLOVERS trial, comparing an early vasopressor with early fluids strategy in patients with sepsis-induced hypotension. Co-chief investigator Ivor Douglas, from Colorado, USA, will present the trial. Our second trial is AID-ICU, a fascinating trial evaluating haloperidol in ICU patients with delirium. Nina Christine Andersen-Ranberg, the co-ordinating investigator, from Copenhagen, Denmark, will present the trial. We have two massive trials to announce this week - watch this space!
Support CCR
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Research
Randomised Controlled Trials
- Welzel. Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial. Lancet Child Adolesc Health 2023;epublished February 3rd
- Chen. Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke. The ARAIS Randomized Clinical Trial. JAMA 2023;epublished February 9th
- Gahan. Closed versus open endotracheal tube suction in mechanically ventilated neonates: a randomized controlled trial. Eur J Pediatr 2023;182(2):785-793
- Kanamori. Effect of intraoperative systemic magnesium sulphate on postoperative Richmond Agitation-Sedation Scale score after endovascular repair of aortic aneurysm under general anesthesia: A double-blind, randomized, controlled trial. PLoS One 2023;18(2):e0281457
- Pan. The low-dose colchicine in patients after non-CABG cardiac surgery: a randomized controlled trial. Crit Care 2023;27:49
Systematic Review & Meta Analyses
- Gelormini. Brain tissue oxygenation monitoring in subarachnoid hemorrhage for the detection of delayed ischemia: a systematic review and meta-analysis. Minerva Anestesiologica 2023;89(1-2):96-103
- Lee. Benefits and harm of probiotics and synbiotics in adult critically ill patients. A systematic review and meta-analysis of randomized controlled trials with trial sequential analysis. Clin Nutrition 2023;epublished February 6th
- Zhu. Early versus delayed minimally invasive intervention for acute necrotizing pancreatitis: An updated systematic review and meta-analysis. Dig Surg 2023;epublished February 7th
- Hofmaenner. Association Between Hypocholesterolemia and Mortality in Critically Ill Patients With Sepsis: A Systematic Review and Meta-Analysis. Crit Care Explor 2023;5(2):e0860
- Tavares. Early tracheostomy versus late tracheostomy in severe traumatic brain injury or stroke: A systematic review and meta-analysis. Aust Crit Care 2023;epublished February 10th
Observational Studies
- Meyer. Epileptic Status in a PEDiatric cohort (ESPED) requiring intensive care treatment: a multicenter, national, two-year prospective surveillance study. Epilepsia Open 2023;epublished February 10th
- Tabah. Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study. Intensive Care Med 2023;epublished February 10th
- Obara. Association of Prehospital Physician Presence During Pediatric Out-of-Hospital Cardiac Arrest With Neurologic Outcomes. Pediatr Crit Care Med 2023;epublished February 8th
- Liu. Comparison of the Montreux definition with the Berlin definition for neonatal acute respiratory distress syndrome. Eur J Pediatr 2023;epublished February 3rd
- Gundersen. PrehospitaL Ultrasound in Undifferentiated DyspnEa (PreLUDE): a prospective, clinical, observational study. Scand J Trauma Resusc Emerg Med 2023;31(1):6
Guidelines
- The International Society for Heart and Lung Transplantation/Heart Failure Society of America Guideline on Acute Mechanical Circulatory Support. J Heart Lung Transplant 2022;epublished February 6th
- Sarkar. Clinical Practice Guidelines for Assessment and Management of Patients with Substance Intoxication Presenting to the Emergency Department. Indian J Psychiatry 2023;65(2):196-211
- Boerwinkle. Proceedings of the First Pediatric Coma and Disorders of Consciousness Symposium by the Curing Coma Campaign, Pediatric Neurocritical Care Research Group, and NINDS: Gearing for Success in Coma Advancements for Children and Neonates. Neurocrit Care 2023;epublished February 9th
Reviews
Clinical
COVID-19
- Chang. Effect of extracorporeal hemoadsorption in critically ill patients with COVID-19: A narrative review. Front Immunol 2023;14:1074465
- Alessandri. Extracorporeal membrane oxygenation for COVID-19-related acute respiratory distress syndrome: a narrative review. J Intensive Care 2023;11:5
- Singh. Review of COVID-19 Management Guidelines. Asian J Research Infect Dis 2023;12(2):33-49
Neurological
- Tokuda. Sepsis-Associated Delirium: A Narrative Review. J Clin Med 2023;12:1273
- Palaniswamy. Anesthetic considerations and care management of children with traumatic brain injury. J Pediatr Neurosci 2023;epublished February 8th
Circulatory
- Kim. Antiarrhythmic drugs and anaesthesia. Part 2: pharmacotherapy. BJA Education 2023;23(2):52-60
- Chakraborty. Discontinuation of ECMO—a review with a note on Indian scenario. Indian J Thorac Cardiovasc Surg 2023;epublished February 4th
- Miao. The role of metabolomics in myocardial infarction: a recent mini-review. Signa Vitae 2023;19(1):34-42
Respiratory
- Cammarota. Advanced Point-of-care Bedside Monitoring for Acute Respiratory Failure. Anesthesiology 2023;138:317–334
- Collins. Physiological adaptations during weaning from veno-venous extracorporeal membrane oxygenation. ICMx 2023;11:7
- Ndubisi. Veno-venous extracorporeal membrane oxygenation for the treatment of respiratory compromise. Indian J Thorac Cardiovasc Surg 2023;epublished February 8th
- Bai. A narrative review of progress in the application of artificial intelligence in acute respiratory distress syndrome: subtypes and predictive models. Ann Translat Med 2023;11(2):128
- Oh. Role of echocardiography in acute pulmonary embolism. Korean J Intern Med 2023;:kjim.2022.273
- Theerawit. An importance of respiratory drive and effort during mechanical ventilation: Respiratory drive and effort in respiratory failure. Clin Crit Care 2023;31(1):2023:e0001
Nutrition
- Duan. Nutritional support in the acute phase of critical illness—how to break the dilemma. Signa Vitae 2023;19(1):9-14
- Prado. Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient. J Parenter Enteral Nutr. 2023;47:S54–S68
Renal
- Yun. Evaluation and management of hypernatremia in adults: clinical perspectives. Korean J Intern Med 2022;:kjim.2022.346
- Peng. Acute Cardiorenal Syndrome: Epidemiology, Pathophysiology, Assessment, and Treatment. Rev Cardiovasc Med 2023;24(2):40
Endocrine
Haematological
- Zohair. Management of acute hemorrhage in patients with hemophilia or von Willebrand disease in the emergency department. Signa Vitae 2023;19(1):1-8
- Karki. Red cell transfusion in critical care: Could less be more?. Journal of Nepalese Society of Critical Care Medicine 2023;1(1):17–22
Sepsis
- Ronco. Rationale for sequential extracorporeal therapy (SET) in sepsis. Crit Care 2023;27:50
- Leistner. Skin Infections Due to Panton-Valentine Leukocidin–Producing S. Aureus. Dtsch Arztebl Int 2022;119:775-84
- Kidd. Fungal Nomenclature: Managing Change is the Name of the Game. Open Forum Infect Dis 2023;10(1):ofac559
- Tullo. Ultrasound in Sepsis and Septic Shock—From Diagnosis to Treatment. J Clin Med 2023;12:1185
- Li. Recent application of metabolomics in the diagnosis, pathogenesis, treatment, and prognosis of sepsis. Signa Vitae 2023;19(1):15-22
- Letafati. Monkeypox virus: A review. Microbial Pathogenesis 2023;176:106027
Trauma
Paediatrics
- Cools. Rapid sequence induction in Paediatric Anaesthesia: A narrative review. Trends Anaesth Crit Care 2023;49:101215
- Shahid. Pediatric Pericarditis: Update. Curr Cardiol Rep 2023;epublished February 7th
Perioperative
Miscellaneous
- Chelazzi. The adult and pediatric palliative care: differences and shared issues. J Anesth Analg Crit Care 2023;3:1
- Old. Entering the new digital era of intensive care medicine: an overview of interdisciplinary approaches to use artificial intelligence for patients’ benefit. Eur J Anaesthesiol Intensive Care 2023;2(1):e0014
- Tin. Hybrid warfare and counter-terrorism medicine. Eur J Trauma Emerg Surg (2023;epublished February 10th
Pre-Clinical
Editorials
- Wang. Early Mobilization in the ICU: to Rest or to Test? J Cardiothorac Vasc Anaesth 2023;epublished February 8th
- Townsley. Methylprednisolone for Heart Surgery in Infants: Findings from a Large-scale, Randomized, Controlled Trial. J Cardiothorac Vasc Anaesth 2023;epublished February 8th
- Harvey. Growing pains: Opportunity knocks in the 2022 CDC Clinical Practice Guidelines for prescribing opioids for pain. J Cardiothorac Vasc Anesth 2023;epublished February 7th
- Monteiro. Are circulating endothelial cells the next target for transcriptome-level pathway analysis in ARDS? Am J Physiol Lung Cell Mol Physiol 2023;epublished February 7th
- Bonovas. On p-Values and Statistical Significance. J Clin Med 2023;12:900
Commentaries
- Truog. The Uncertain Future of the Determination of Brain Death. JAMA 2022;epublished February 7th
- Price. The year in cardiovascular medicine 2022: the top 10 papers in acute cardiac care and ischaemic heart disease. Eur Heart J 2023;44(6):445–447
- Prager. Critical Care Transesophageal Echocardiography for the Resuscitation of Shock. An Important Diagnostic Skill for the Modern Intensivist. Chest 2023;163(2):268-269
- Cheskes. Double sequential external defibrillation for refractory ventricular fibrillation. Intensive Care Med 2023;epublished February 8th
Correspondence
- Hernandez. Post-extubation noninvasive ventilation vs high-flow nasal cannula on reintubation in patients at very high risk for extubation failure. Author’s reply. Intensive Care Med 2023;epublished February 3rd
- Liebchen. The cytokine adsorber Cytosorb® does not reduce ammonia concentrations in critically ill patients with liver failure. Intensive Care Med 2023;epublished February 10th
Case Reports
- Contou. Evolution of purpura fulminans. Intensive Care Med 2023;epublished February 6th
- Schluger. A 25-Year-Old Patient With Chest Wall Erythema and Tenderness Who Was Ventilated Mechanically. Chest 2023;163(2):e57-e61
- Smoot. A Woman With Progressive Dyspnea and Seronegative Rheumatoid Arthritis. Chest 2023;163(2):e63-e67
- Thang. A 44-Year-Old Man With Chronic Lower Chest Pain. Chest 2023;163(2):e69-e72
- Fong. A 44-Year-Old Woman With Prolonged Fever and Mediastinal “Lymphadenopathy”. Chest 2023;163(2):e73-e78
- Jarnagin. An 80-Year-Old Woman With Dyspnea and a Lung Mass. Chest 2023;163(2):e79-e82
- Moore. A 53-Year-Old With Progressive Dyspnea. Chest 2023;163(2):e83-e89
- Ruddy. A Rare Case of Cardiogenic Shock Induced by Choking. Chest 2023;163(2):e91-e95
- Maxwell. Air Where? An Ominous Finding on Point-of-Care Ultrasound Scanning. Chest 2023;163(2):e97-e99
- Tom. A 73-Year-Old Woman With a Bounding Barrier to Tracheostomy. Chest 2023;163(2):e101-e103
- Abazid. Thrombus in Transit Entrapped Within a Patent Foramen Ovale: Role of Multimodality Imaging. CASE 2023;epublished February 7th
- Laici. Planned Extracorporeal Life Support Employment during Liver Transplantation: The Potential of ECMO and CRRT as Preventive Therapies—Case Reports and Literature Review. J Clin Med 2023;12:1239
- Sharma. Double doughnut sign in dengue encephalitis. Journal of Nepalese Society of Critical Care Medicine 2023;1(1):26-27
I hope you find this newsletter useful.
Until next week
Rob