- Neuro
- Circulatory
- Resuscitation
- Airway
- Respiratory
- GI
- Nutrition
- Liver
- Renal
- Haem
- Sepsis
- Paediatrics
- Perioperative
- Miscellaneous
- Meng. Tenecteplase vs Alteplase for Patients With Acute Ischemic Stroke. The ORIGINAL Randomized Clinical Trial. JAMA 2024;332(17):1437-1445
- Taccone. Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury. The TRAIN Randomized Clinical Trial. JAMA 2024;epublished October 9th
- Greer. Fever Prevention in Patients With Acute Vascular Brain Injury. The INTREPID Randomized Clinical Trial. JAMA 2024;epublished September 25th
- The Writing Committee for the TESLA Investigators. Thrombectomy for Stroke With Large Infarct on Noncontrast CTThe TESLA Randomized Clinical Trial. JAMA 2024;epublished September 23rd
- Liu. Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial. Intensive Care Med 2024;epublished September 23rd
- Meng. Tenecteplase vs Alteplase for Patients With Acute Ischemic Stroke: The ORIGINAL Randomized Clinical Trial. JAMA 2024;epublished September 12th
- Adeoye. Adjunctive Intravenous Argatroban or Eptifibatide for Ischemic Stroke. N Engl J Med 2024;391:810-820
- Deschamps. Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery. The ENGAGES-Canada Randomized Clinical Trial. JAMA 2024;332(2):112-123
- Turgeon.Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury. N Eng J Med 2024;epublished June 13th
- Taboada. First-attempt awake tracheal intubation success rate using a hyperangulated unchannelled videolaryngoscope vs. a channelled videolaryngoscope in patients with anticipated difficult airway: a randomised controlled trial. Anaesthesia 2024;epublished July 29th
- Gibbs. Noninvasive Ventilation for Preoxygenation during Emergency Intubation. N Eng J Med 2024;epublished June 13th
- Geraghty. Video versus Direct Laryngoscopy for Urgent Intubation of Newborn Infants. N Engl J Med 2024;epublished May 5th
- Ruetzler. Video Laryngoscopy vs Direct Laryngoscopy for Endotracheal Intubation in the Operating Room. A Cluster Randomized Clinical Trial. JAMA 2024;epublished March 18th
- Burns. Frequency of Screening and Spontaneous Breathing Trial Techniques. A Randomized Clinical Trial. JAMA 2024;epublished October 9th
- Mascia. Lung protective mechanical ventilation in severe acute brain injured patients: a multicenter, randomized clinical trial (PROLABI). Am J Respir Crit Care Med 2024;epublished September 17th
- Ekström. Long-Term Oxygen Therapy for 24 or 15 Hours per Day in Severe Hypoxemia. N Engl J Med 2024;epublished September 10th
- Devereux. Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial. JAMA 2024;332(6):462-470
- Liu. Prolonged vs shorter awake prone positioning for COVID-19 patients with acute respiratory failure: a multicenter, randomised controlled trial. Intensive Care Med 2024;epublished August 1st
- Tan. High flow nasal cannula oxygen therapy versus non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: a randomized controlled non-inferiority trial. Crit Care 2024;28:250
- Nielsen. Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19. The HOT-COVID Randomized Clinical Trial. JAMA 2024;epublished March 19th
- Bels. Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe): an investigator-initiated, double-blinded, multicentre, parallel-group, randomised controlled trial in Belgium and the Netherlands. Lancet 2024;404(10453):659-669
- Wang. Impact of early high protein intake in critically ill patients: a randomized controlled trial. Nutr Metab 2024;21:39
- Pérez-Fernández. Extracorporeal Blood Purification and Acute Kidney Injury in Cardiac Surgery. The SIRAKI02 Randomized Clinical Trial. JAMA 2024;epublished October 9th
- Jia. Effect of Delayed Remote Ischemic Preconditioning on Acute Kidney Injury and Outcomes in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial. Circulation 2024;epublished September 25th
- Parapiboon. Lower-Dosage Acute Peritoneal Dialysis versus Acute Intermittent Hemodialysis in Acute Kidney Injury. A Randomized Controlled Trial. Clin J Am Soc Nephrol 2024;19(8):970-977
- Panwar. A multicenter randomized controlled trial comparing three-times-a-day intermittent enteral postural feeding to continuous enteral feeding among mechanically ventilated patients in Intensive Care. Clinical Nutr 2024;epublished July 31st
- Landoni. A Randomized Trial of Intravenous Amino Acids for Kidney Protection. N Eng J Med 2024;epublished June 12th
- Pickkers. Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL). Intensive Care Med 2024;epublished January 3rd
- Taccone. Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury. The TRAIN Randomized Clinical Trial. JAMA 2024;epublished October 9th
- Sarode. Vitamin K Antagonist Reversal for Urgent Surgery Using 4-Factor Prothrombin Complex ConcentratesA Randomized Clinical Trial. JAMA Netw Open 2024;7(8):e2424758
- Turgeon.Liberal or Restrictive Transfusion Strategy in Patients with Traumatic Brain Injury. N Eng J Med 2024;epublished June 13th
- Bestle. Iloprost and Organ Dysfunction in Adults With Septic Shock and Endotheliopathy: A Randomized Clinical Trial. JAMA Netw Open 2024;7(9):e2432444
- Birbeck. Acetaminophen and Ibuprofen in Pediatric Central Nervous System Malaria. A Randomized Clinical Trial. JAMA Neurol 2024;81(8):857-865
- Wu. Effect of Metagenomic Next-Generation Sequencing on Clinical Outcomes of Patients with Severe Community-Acquired Pneumonia in ICU: A Multicenter Randomized Controlled Trial. Chest 2024;epublished July 24th
- AL-regal. Dexmedetomidine for reducing mortality in patients with septic shock: A randomized controlled trial (DecatSepsis). Chest 2024;epublished July 11th
- Freund. Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial. Intensive Care Med 2024;epublished June 24th
- Dulhunty. Continuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis. The BLING III Randomized Clinical Trial. JAMA 2024;epublished June 12th
- López-Cortés. Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial. Lancet Respir Dis 2024;epublished January 9th
- Boisson. Chlorhexidine-alcohol compared with povidone-iodine-alcohol skin antisepsis protocols in major cardiac surgery: a randomized clinical trial. Intensive Care Med 2024;epublished November 12th
- O’Brien. Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery. The TIGHT K Randomized Clinical Trial. JAMA 2024;epublished August 31st
- Legrand. Continuation vs Discontinuation of Renin-Angiotensin System Inhibitors Before Major Noncardiac Surgery. The Stop-or-Not Randomized Clinical Trial. JAMA 2024;epublished August 30th
- Karanicolas. Tranexamic Acid in Patients Undergoing Liver Resection. The HeLiX Randomized Clinical Trial. JAMA 2024;epublished August 19th
- Lopez. Intraoperative Oxygen Treatment, Oxidative Stress, and Organ Injury Following Cardiac Surgery: A Randomized Clinical Trial. JAMA Surg 2024;epublished August 7th
- Nicklas. Personalised blood pressure management during major noncardiac surgery and postoperative neurocognitive disorders: a randomised trial. BJA Open 2024;11:100294
- Cihoric. Preoperative high dose of dexamethasone in emergency laparotomy: randomized clinical trial. Br J Surg 2024;111(7):znae130
- Deschamps. Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery. The ENGAGES-Canada Randomized Clinical Trial. JAMA 2024;332(2):112-123
- Widmer. Povidone Iodine vs Chlorhexidine Gluconate in Alcohol for Preoperative Skin Antisepsis. A Randomized Clinical Trial. JAMA 2024;epublished June 17th
- Myles. Dexamethasone for Cardiac Surgery: A Practice Preference-Randomized Consent Comparative Effectiveness Trial. Anesthesiology 2024;epublished June 21st
- Pereira. Effect of Tele-ICU on Clinical Outcomes of Critically Ill Patients. The TELESCOPE Randomized Clinical Trial. JAMA 2024;epublished October 9th
- Benoit. Coaching doctors to improve ethical decision-making in adult hospitalized patients potentially receiving excessive treatment. The CODE stepped-wedge cluster randomized controlled trial. Intensive Care Med 2024;epublished September 4th
- Tavares. Dapagliflozin for Critically Ill Patients With Acute Organ Dysfunction. The DEFENDER Randomized Clinical Trial. JAMA 2024;epublished June 14th
Rehab
- Zhang. Impact of Adding Bedside Cycling to Intensive Care Unit Rehabilitation on Physical Function and Length of Stay After Liver Transplantation: A Randomized Controlled Trial. Transplant Proc 2024;epublished September 5th
- Kho. Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients. NEJM Evidence 2024;epublished June 12th
Last updated March 25th, 2024