General
General
General
- Zhang. Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management. MedComm. 2026;7(4):e70704.
- Lo. Advances in ischemic stroke treatment: current and future therapies. Neurol Ther 2025;epublished August 13th
- Rapp. Updated Review of the Management of and Guidelines for Traumatic Brain Injury. J Clin Med. 2025;14(19):6796.
- Ho. Contemporary Management of Acute Ischemic Stroke. Annu Rev Med 2025;76:417–29
- Bogenschutz. Acute ischemic stroke: a guideline-based overview of evaluation and management. JAAPA 2025;38(5):13-20
- Arnalich-Montiel. Comprehensive management of stroke: from mechanisms to therapeutic approaches. Int J Mol Sci 2024;25(10):5252
- Mead. A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization. Int J Stroke 2023;18(5):499-531
- Saceleanu. Integrative approaches in acute ischemic stroke: from symptom recognition to future innovations. Biomedicines 2023;11(10):2617
Therapeutic Paradigm
Artificial Intelligence
- Brooks. The Role of Artificial Intelligence in Acute Ischemic Stroke Care: A Narrative Review. Mo Med. 2026;123(3):234-242.
- Parvathy. Emerging artificial intelligence-aided diagnosis and management methods for ischemic strokes and vascular occlusions: A comprehensive review. World Neurosurg X. 2024;22:100303.
Stroke Types
Hemispheric
Posterior Circulation
Tandem Occlusions
Background
Pathophysiology
- Kleeberg. Endothelial dysfunction in acute ischemic stroke: a review. J Neurol 2025;272(2):143
- Sasannia. Blood-brain barrier breakdown in brain ischemia: insights from MRI perfusion imaging. Neurotherapeutics 2025;22(1):e00516
- Salaudeen. Understanding the pathophysiology of ischemic stroke: the basis of current therapies and opportunity for new ones. Biomolecules 2024;14(3):305
- Alsbrook. Neuroinflammation in acute ischemic and hemorrhagic stroke. Curr Neurol Neurosci Rep 2023;23(8):407-431
Conditions
Pulmonary Embolism
Atrial Fibrillation
Paediatrics & Neonatology
Patent Foramen Ovale
Complications
No-Reflow
- Zhang. "No-reflow" phenomenon in acute ischemic stroke. J Cereb Blood Flow Metab 2024;44(1):19-37
- Sun. No-reflow after recanalization in ischemic stroke: from pathomechanisms to therapeutic strategies. J Cereb Blood Flow Metab 2024;44(6):857-880
- Hu. Microcirculation no-reflow phenomenon after acute ischemic stroke. Eur Neurol 2023;86(2):85-94
- Nie. Clinically ineffective reperfusion after endovascular therapy in acute ischemic stroke. Stroke 2023;54(3):873-881
Haemorrhagic Transformation
Cardiac Complications
- Gao. Cardio-cerebral infarction: a narrative review of pathophysiology, treatment challenges, and prognostic implications. Front Cardiovasc Med. 2025;12:1507665.
- Mitrică. The Hidden Heart: Exploring Cardiac Damage Post-Stroke: A Narrative Review. Medicina 2024;60(10):1699
- Fan. Stroke Related Brain–Heart Crosstalk: Pathophysiology, Clinical Implications, and Underlying Mechanisms. Adv Sci 2024;2307698
- Scheitz. Stroke-Heart Syndrome: Recent Advances and Challenges. J Am Heart Assoc 2022;11(17):e026528
Investigations & Monitoring
Imaging
Diagnosis
- Broocks. Current perspective in acute ischemic stroke: net water uptake and imaging-guided selection as bridges to personalized, tissue-based care. Front Neurol. 2026;16:1741898.
- Samaniego. Priorities for advancements in neuroimaging in the diagnostic workup of acute stroke. Stroke 2023;54(12):3190-3201
- Nukovic. Neuroimaging modalities used for ischemic stroke diagnosis and monitoring. Medicina 2023;59(11):1908
- Hua. Definition, prediction, prevention and management of patients with severe ischemic stroke and large infarction. Chin Med J 2023;136(24):2912-2922
General
Cryptogenic
Other
Biomarkers
Post Stroke
Therapies
General
- Wang. Current status and advances in comprehensive treatment of acute ischemic stroke in China: from evidence-based guidelines to clinical practice. Front Neurol. 2026;17:1751280.
- Palaiodimou. Drip and ship in patients with acute ischemic stroke: a narrative review. Ther Adv Neurol Disord 2025;18:17562864251378833
- Kargiotis. Tailored Treatment of Acute Ischemic Stroke: A Narrative Review of Evidence-Based Strategies by Imaging Type and Thrombectomy Availability. Medicina 2025;61(9):1700.
- Sharma. Advances in treatments for acute ischemic stroke. BMJ 2025;389:e076161
- Cheng. Time and tissue windows in futile reperfusion after ischemic stroke. Aging Dis 2024;16(5):2544-2552
- Bathla. Advances in acute ischemic stroke treatment: current status and future directions. AJNR Am J Neuroradiol 2023;44(7):750-758
- Widimsky. Acute ischaemic stroke: recent advances in reperfusion treatment. Eur Heart J 2023;44(14):1205-1215
Blood Pressure Control
- Shah. Blood Pressure Variability in Acute Ischemic Stroke: Current Evidence, Measurement Challenges, and Future Directions. J Clin Hypertens 2026;28(7):e70322.
- Liu. Blood Pressure Management Pre- and Post-Reperfusion in Acute Ischemic Stroke: Evidence and Insights from Recent Studies. Curr Neurol Neurosci Rep 2025;25:52
- Zompola. Blood Pressure Variability in Acute Stroke: A Narrative Review. J Clin Med. 2024;13(7):1981
- Gąsecki. Blood Pressure Management in Acute Ischemic Stroke. Curr Hypertens Rep 2021;23:3
Thrombolysis
- Moore. Critical Care After Thrombolytic Therapy in Acute Stroke: Who Really Needs the ICU? J Clin Med. 2026;15(1):324
- Zupan. Tenecteplase—What Have We Learned till Now? A Narrative Review. Life 2025;15(9):1356
- Silva. Tenecteplase in acute ischemic stroke: a new era in thrombolysis. Arq Neuropsiquiatr 2025;83(5):1-11
- Wang. Comprehensive review of tenecteplase for thrombolysis in acute ischemic stroke. J Am Heart Assoc 2024;13(9):e031692
- Donaldson. The changing landscape of intravenous thrombolysis for acute ischaemic stroke. J Clin Med 2024;13(19):5826
- Miller. Evolving thrombolytics: from alteplase to tenecteplase. Neurotherapeutics 2023;20(3):664-678
- Pan. Silver Jubilee of Stroke Thrombolysis With Alteplase: Evolution of the Therapeutic Window. Front Neurol 2021;12:593887
Endovascular Therapy
- Sarraj. Mechanical thrombectomy for large ischemic stroke: a critical appraisal of evidence from 6 randomized controlled trials. Stroke 2025;56(7):1917-1927
- Mutimer. Current perspectives on endovascular therapy for large core ischemic stroke. Neurotherapeutics. 2025;22(4):e00622.
- Ospel. Endovascular treatment of medium vessel occlusion stroke. Stroke 2024;55(3):769-778
- Raha. Advances in mechanical thrombectomy for acute ischaemic stroke. BMJ Medicine 2023;2:e000407
- Parvathy. Mechanical thrombectomy for AIS from large vessel occlusion - current trends and future perspectives. Ann Med Surg 2023;85(12):6021-6028
- Kaneko. Devices and techniques. J Neuroendovasc Ther 2023;17(11):257-262
Future Therapies
Antithrombotics
Neuro Protection
- Dammavalam. Neuroprotection during thrombectomy for acute ischemic stroke: a review of future therapies. Int J Mol Sci 2024;25(2):891
- Zhao. Multi-target and multi-phase adjunctive cerebral protection for acute ischemic stroke in the reperfusion era. Biomolecules 2024;14(9):1181
- Zhao. Neuroprotective strategies in acute ischemic stroke: A narrative review of recent advances and clinical outcomes. Brain Circ 2024;10(4):296-302
- Haupt. Neuroprotective strategies for ischemic stroke-future perspectives. Int J Mol Sci 2023;24(5):4334
Antiplatelets
Anticoagulation
Chronic Management
Magnesium Sulphate
Temperature Management
Last updated August 3rd, 2026