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Critical Care Reviews Newsletter
Newsletter 591 | April 9th, 2023
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A Massive Paediatric Trial Results Presentation to be added to the CRR23 Programme Tomorrow
Welcome to the 591st Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
This week we announced two more fantastic trial result presentations for the Critical Care Reviews Meeting 2023. Glenn Eastwood and Alistair Nichol will deliver the results of the TAME cardiac arrest trial, examining targeted therapeutic mild hypercapnia after resuscitated cardiac arrest. Karim Brohi will give the results of the CRYOSTAT-2 trial, evaluating early high-dose cryoprecipitate in adult patients with major traumatic haemorrhage. Tomorrow (Monday, April 10th), we announce our sixth major trial result presentation, this time a massive paediatric trial.
In addition to TAME & CRYOSTAT-2, we are also hosting the results presentations of the first RCT of the REBOA device, the UK REBOA Trial; the 2000 patient American video versus direct laryngoscope trial, DEVICE; and the international PATCH-Trauma trial, examining prehospital tranexamic acid in severe trauma. We'll also review some of the best trials presented over the past year, including AID-ICU (haloperidol for delirium), TEAM (early mobilisation), CLOVERS (early vasopressors in sepsis), PILOT (oxygenation targets) and the 180 day outcomes of the COVID-19 domains of the REMAP-CAP trial. We still have some further trials to add as well as our panel discussions. If you're interested in the evidence that informs our clinical practice, join us in June for the best critical care trials in the world.
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Research
Randomised Controlled Trials
- Sarraj. Trial of Endovascular Thrombectomy for Large Ischemic Strokes. N Engl J Med 2023;388:1259-1271.
- Huo. Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct. N Engl J Med 2023;388:1272-1283.
- Badovinac. Tranexamic Acid vs Adrenaline for Controlling Iatrogenic Bleeding During Flexible Bronchoscopy: A Double-Blind Randomized Controlled Trial. Chest. 2023;163(4):985-993
- Rizvi. Intravenous immunoglobulin in the management of neonatal sepsis: A randomised controlled trial. Trop Doct. 2023;53(2):222-226
Systematic Review & Meta Analyses
- Boscolo. Noninvasive respiratory support after extubation: a systematic review and network meta-analysis. Eur Respir Rev 2023;32(168):220196.
- Brokmeier. Hydroxocobalamin for Vasodilatory Hypotension in Shock: A Systematic Review with Meta Analysis for the Comparison to Methylene Blue. J Cardiothorac Vasc Anesth 2023;epublished April 7th
- Wang. Balanced crystalloid solutions versus normal saline in intensive care units: a systematic review and meta-analysis. Int Urol Nephrol 2023;epublished April 5th
- Premraj. Tracheostomy timing and outcome in critically ill patients with stroke: a meta-analysis and meta-regression. Crit Care 2023;27:132
- Kawasuji. Effectiveness and Safety of Linezolid Versus Vancomycin, Teicoplanin, or Daptomycin against Methicillin-Resistant Staphylococcus aureus Bacteremia: A Systematic Review and Meta-Analysis. Antibiotics 2023;12(4):697
- Li. High-flow nasal cannula reduces intubation rate in patients with COVID-19 with acute respiratory failure: a meta-analysis and systematic review. BMJ Open 2023;13(3):e067879
Observational Studies
- Sonneville. Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study. Intensive Care Med. 2023;epublished April 6th.
- Martin. Days Spent at Home and Mortality After Critical Illness: A Cluster Analysis Using Nationwide Data. Chest 2023;163(4):826-842.
- Prekker. Laryngoscopy and Tracheal Intubation: Does Use of a Video Laryngoscope Facilitate Both Steps of the Procedure? Ann Emerg Med 2023;S0196-0644(23)00126-9.
- Angriman. LOVIT Investigators Collaborators. IV Vitamin C in Adults With Sepsis: A Bayesian Reanalysis of a Randomized Controlled Trial. Crit Care Med 2023;epublished April 7th
- Sabir. Feasibility of bedside portable MRI in neonates and children during ECLS. Crit Care 2023;27:134
- Esmail. Sharing of Individual Patient-Level Data by Trialists of Randomized Clinical Trials of Pharmacological Treatments for COVID-19. JAMA 2023;epublished April 3rd
- Snider. Clinical and Electroencephalographic Predictors of Seizures and Status Epilepticus in 12,450 Critically Ill Adults: A Retrospective Cohort Study. Crit Care Med 2023;epublished April 3rd
- van Veen. Comparative Effectiveness of Mannitol versus Hypertonic Saline in Traumatic Brain Injury patients: a CENTER-TBI study. J Neurotrauma 2023;epublished April 4th
- Rahimi. The Effect of Time to Treatment With Antiarrhythmic Drugs on Survival and Neurological Outcomes in Shock Refractory Out-of-Hospital Cardiac Arrest. Crit Care Med 2023;epublished April 4th
- Felton TW, Ahmed W, White IR, et al. Analysis of exhaled breath to identify critically ill patients with ventilator-associated pneumonia. Anaesthesia 2023;epublished April 3rd
Guidelines
- Neuroprognostication in the Post Cardiac Arrest Patient: A Canadian Cardiovascular Society Position Statement. Can J Cardiol 2023;39(4):366-380
- Dimairo. The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ 2020;369:m115
- ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia. Intensive Care Med 2023;epublished April 4th
- Regional citrate anticoagulation (RCA) in critically ill patients undergoing renal replacement therapy (RRT): expert opinion from the SIAARTI-SIN joint commission. J Anesth Analg Crit Care 2023;3:7
Reviews
Clinical
COVID-19
Neurological
Circulatory
- Frampton. Arrhythmias After Acute Myocardial Infarction. Yale J Biol Med 2023;96(1):83-94
- Kan. Current Commonly Used Dynamic Parameters and Monitoring Systems for Perioperative Goal-Directed Fluid Therapy: A Review. Yale J Biol Med 2023;96(1):107-123
- Hill. Cardiogenic Shock Classification and Associated Mortality Risk. Mayo Clin Proc 2023;epublished April 5th
- Samad. Natriuretic Peptides as Biomarkers: Narrative Review and Considerations in Cardiovascular and Respiratory Dysfunctions. Yale J Biol Med 2023;96(1):137-149
- Bart. The role of frailty in advanced HF and cardiac transplantation. Front Cardiovasc Med 2023;10:1082371
- Smith. The Evolution of Durable, Implantable Axial-Flow Rotary Blood Pumps. Tex Heart Inst J 2023;50(2):e227908.
Respiratory
- See. Acute management of pneumonia in adult patients. Singapore Med J. 2023;64(3):209–216
- Bureau. Managing respiratory muscle weakness during weaning from invasive ventilation. Eur Respir Rev 2023;32(179):220205
- Shah. New Drugs and Therapies in Pulmonary Arterial Hypertension. Int J Mol Sci. 2023;24(6):5850
Renal
- Kanbay. Intravenous fluid therapy in accordance with kidney injury risk: when to prescribe what volume of which solution. Clin Kidney J 2022;16(4):684-692
- Rosner. Acquired Disorders of Hypomagnesemia. Mayo Clin Proc 2023;98(4):581-596
- Zhou. Reducing Oxygen Demand to Alleviate Acute Kidney Injury. Front Biosci 2023;28(3):62
Sepsis
Miscellaneous
Editorials
Commentaries
- Robba. Acute respiratory distress syndrome complicating traumatic brain injury. Can opposite strategies converge? Intensive Care Med 2023;epublished August 5th.
- Ridley. NUTRIREA-3: where to next? Lancet Respir Med 2023;epublished April 4th
- Zhou. The comforting companion: using AI to bring loved one's voices to newborns, infants, and unconscious patients in ICU. Crit Care 2023;27:135.
- Lieberman. Reexamining cholinesterase inhibitors for the prevention and treatment of delirium in high-risk populations. Crit Care 2023;27:129.
- Stern. It's Like a Death. JAMA 2023;329(13):1061-1062.
- Rubin. It Takes an Average of 17 Years for Evidence to Change Practice—the Burgeoning Field of Implementation Science Seeks to Speed Things Up. JAMA 2023;epublished April 5th
Correspondence
Case Reports
- Datta. A 54-Year-Old Woman With Rheumatoid Arthritis, Low-Grade Fever, and Cough. Chest 2023;163(4):e151-e155
- Liu. A 49-Year-Old Woman With Exertional Dyspnea and Dizziness. Chest 2023;163(4):e157-e162
- Ferioli. A 60-Year-Old Man With a Migratory Lobar Consolidation After Invasive Ventilation. Chest 2023;163(4):e163-e166
- Tehzeeb. A 21-Year-Old Hispanic Woman Presenting With Cutaneous and Pulmonary Nodules. Chest 2023 Apr;163(4):e167-e171
- Fox. Pleural Infection and Gastric Distension: Finding the Connection With Sonographic Inspection. Chest 2023 Apr;163(4):e173-e177
- Andrea. A 62-Year-Old Man With Elevated Creatinine and Disappearing Ascites. Chest 2023;163(4):e179-e181
- Szekely. The "Fish Tank". Chest 2023;163(4):e183-e185
- Cheng. A 35-Year-Old Man With Fever and Pulmonary Cavity. Chest. 2023 Apr;163(4):e187-e191
- Marell. Acute Pontine Osmotic Demyelination Syndrome at Presentation of Lymphoma in Association With. Mayo Clin Proc 2023;98(4):507-508
- Chen. Refractory hyponatremia after cervical spinal-cord injury: A case report. Asian J Surg 2023;46(4):1598-1599
I hope you find this newsletter useful.
Until next week
Rob